TOPICLO-B Cream

Clotrimazole & Beclomethasone Cream contains the dipropionate ester of betamethasone, a glucocorticoid exhibiting the general properties of corticosteroids, and clotrimazole which is an imidazole antifungal agent. Topical corticosteroids are effective in the treatment of a range of dermatoses because of their anti-inflammatory anti-pruritic and vasoconstrictive actions. Clotrimazole is a broad-spectrum antifungal agent with activity against Trichomones, Staphylococci and Bacteroides.

Clotrimazole & Beclomethasone Cream is intended for treatment of skin conditions and is applied topically. Thus, there are minimal pharmacokinetic aspects related to bioavailability at the site of action. Clotrimazole penetrates the epidermis after topical administration but there is little, if any, systemic absorption. The extent of percutaneous absorption of topical corticosteroids is determined by many factors including vehicle, integrity of skin and use of occlusion. Systemically absorbed topical corticosteroids are bound to plasma proteins metabolised in the liver and excreted by the kidneys. Some corticosteroids and their metabolites are also excreted in the bile.

Adults and children over the age of 12 years. Topical administration twice daily for two weeks (tinea cruris, tinea corporis and candidiasis) or for four weeks (tinea pedis). Paediatric population Clotrimazole & Beclomethasone cream is not recommended for children under the age of twelve years. Method of administration Topical administration only.

TOPICLO-B Cream is available in 15 g of pack filled in laminated tube & packed in carton.