DACK

DACK tablet Diclofenac 50mg

Indication

DACK is indicated for the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.

Mode of Action

The anti-inflammatory effects of DACK are believed to be due to inhibition of leukocyte migration and the enzyme cyclooxygenase (COX-1 and COX-2), leading to the peripheral inhibitor of prostaglandin synthesis. As prostaglandins sensitize pain receptor, inhibition of their synthesis responsible for the analgesic effects of DACK.

Pharmacokinetics

Completely absorbed from the gastrointestinal tract. Volume of distribution is 1.3 L/kg Protein binding: more than 99% Half-life: 2 hours Clearance: 622 mL/min

Dosage and Recommendation

50 mg orally 2 to 3 times a day or 75 mg orally 2 times a day Maximum dose: 150 mg daily

Packing and Presentation

Each strip contains 10 tablets.