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LUCAST

LUCAST

  • Indication
  • Mode of Action
  • Pharmacokinetics
  • Dosage
  • Packing

Prevention and long-term treatment of asthma. It is also used to relieve allergy symptoms (e.g. itchy, runny, or stuffy nose, sneezing) and to prevent asthma attacks caused by exercise.

LUCAST selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1 in the human airway. It inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.

Bioavailability: 64% Volume of distribution: 8 to 11L Protein binding: 99% (to plasma proteins) Half-life: 2.7-5.5 hours

Adult: 10 mg orally once a day. Children – 4 mg orally once a day (orodispersible tablet)

LUCAST is available as a blister strip of 10 tablets in a box of 10 x 10s

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