October 18, 2020
PRAMADOL: Perfect combination for pain relief
The newly launched product of Magnus, PRAMADOL is doing well in the market. As there were only international brands in this segment, Magnus introduced this national brand with most economical value.
PRAMADOL offers improved analgesia due to the different pharmacological targets and synergism along the pain pathway. In fact combining drugs with different mechanisms of action and pharmacokinetic profiles, analgesic efficacy is enhanced even though lower doses of individual drugs are used. Various studies have suggested that the analgesic efficacy is enhanced using multimodal analgesics compared with unimodal analgesic treatment so that one can limit side effects, reduce postoperative pain and analgesic requirements and facilitate an earlier return to normal activities.
The main points of treatment with PRAMADOL are synergism in analgesic effect, reduction of side-effects and a better tolerability for patients. The use of 25% less tramadol in the combination reduces the incidence of tramadol-related adverse events, while the addition of paracetamol quicken the onset of analgesia.